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Built by a practicing doctor · Sources: NHS, NICE, AAOS & more
💛 Friendly guidance: not medical advice💛 Friendly guidance · Always consult your doctorConsult your doctor · Disclaimer
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This page provides general patient information about what radiotherapy is like. It is not medical advice. Radiotherapy varies significantly depending on the cancer type, treatment area, dose, and the individual. Your radiation oncologist and radiotherapy team are your primary source of guidance, their instructions are specific to your treatment and always take priority. Use this page to understand general experiences and to form questions for your team.

Radiotherapy: What you might notice

Radiotherapy (also called radiation therapy) is used to treat many different cancers, either alone or alongside surgery and chemotherapy. Many patients are anxious about what it involves. The reality is that most people tolerate the treatment itself well — the fatigue and skin reactions are the main challenges. This guide explains what to expect.

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Based on guidance from NHS, NICE, AAOS & healthdirect
Last reviewed: July 2026 · Free to use · No data collected
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Radiotherapy can make your skin highly sensitive to UV damage, even weeks after treatment ends. A broad-spectrum SPF 50+ sunscreen helps protect irradiated skin from sunburn and long-term damage. SPF 50+ sunscreen →
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What to expect, stage by stage
Tap a stage to expand its guidance. Radiotherapy is given as a daily course, so stages here follow the course timeline rather than a single countdown. Your checklist progress is remembered on this device.
1 Before Treatment Planning Your Radiotherapy

Radiotherapy typically starts with a planning session (sometimes called simulation): a CT scan used to map the exact area to be treated. Small permanent skin marks or temporary marker dots may be used to line up the machine precisely each day.

2 Week 1 Starting Treatment

Side effects from radiotherapy build up gradually, they are rarely noticeable after just one or two sessions. Most people feel little different in the first week regardless of treatment site.

3 Mid-Course Side Effects Building

By the middle of a course, cumulative effects become more noticeable, skin reactions in the treated area, fatigue, and site-specific effects (for example sore throat if the neck is treated, or bowel changes if the pelvis is treated).

4 Final Week Peak Effects and Finishing

Side effects are typically at their most noticeable in the final week of treatment and the week or two immediately after. This is expected, not a sign of a problem, since effects continue to build for a short time even after the last session.

5 Weeks After Recovery After Treatment Ends

Skin and site-specific effects typically continue to heal over the following weeks to months. Fatigue often lingers longer than people expect: sometimes for weeks after the physical effects have settled.

Sources: NHS · NICE · AAOS · healthdirect
ⓘ Every treatment plan is individual: timing and side effects vary. This does not replace medical advice. Your oncology team's instructions always come first: they know your situation best.

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Content last reviewed: July 2026
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